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					產(chǎn)品展示  / PRODUCTS
					
						藥靶細胞株 > kinase激酶細胞株  >  CBP73298c-Kit L576P/BaF3
            
              
					
				
				
						- 詳細內(nèi)容
 
CBP73298  | |
| I. Introduction | |
Cell Line Name:  | c-Kit L576P/BaF3 | 
Host Cell:  | Ba/F3  | 
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) | 
Application:  | Anti-proliferation assay and PD assay  | 
Freeze Medium:  | 90% FBS+10% DMSO  | 
Complete Culture Medium:  | RPMI-1640+10%FBS  | 
Mycoplasma Status:  | Negative  | 
| II.Background | |
KIT L576P lies within the juxtamembrane domain (exon 11) of the Kit protein (PMID: 17372901). L576P confers a gain of function to Kit, as indicated by constitutive phosphorylation of Kit, and is transforming in cell culture (PMID: 17372901).  | |
| III. Representative Data | |
1. WB of c-Kit L576P/BaF3 
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2. Sanger of c-Kit L576P/BaF3 
 
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3. Anti-proliferation assay  | |
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 Figure 3. CTG Proliferation Assay of BaF3 c-KIT L576P (C6).  | |








