| 名稱(chēng) | TIE2/HEK293 |
| 型號(hào) | CBP74161 |
| 報(bào)價(jià) | ![]() |
| 特點(diǎn) | TIE2/HEK293 |
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電話(huà):4008750250
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手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
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藥靶細(xì)胞株 > 腫瘤免疫細(xì)胞株 > CBP74161TIE2/HEK293
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TIE2/HEK293
| I. Background | |
| TIE2(激酶受體)主要表達(dá)于血管內(nèi)皮細(xì)胞表面的受體,胞外區(qū)含免疫球蛋白 域 ( 結(jié) 合 ANG ) 、 EGF 樣 域 ( 介 導(dǎo) 二 聚 化 ) ; 胞內(nèi)區(qū)含激酶活性位點(diǎn) (Y1100/Y1108)。被配體激活后通過(guò) PI3K/AKT 和 MAPK 通路調(diào)控內(nèi)皮細(xì)胞存活、遷移 及血管屏障功能。在病理狀態(tài)下(如膿毒癥、腫瘤),TIE2 信號(hào)異常導(dǎo)致血管滲漏或異常 增生。 | |
| II. Description | |
| TIE2 HEK293 細(xì)胞,在 HEK293 細(xì)胞的基礎(chǔ)上,穩(wěn)定表達(dá)人 TIE2。 | |
| III. Introduction | |
| Host Cell: | HEK293 |
| Expressed gene: | TIE2 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Synonym(s): | TIE2,Tie-2,TEK,VMCM, VMCM1,CD202b,Angiopoietin-1 receptor ... |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM+10% FBS+2 μg/ml Puromycin |
| Storage: | Liquid nitrogen |
| Application(s): | Binding Assay,FACS |
| IV. Description of Host Cell Line | |
| Organism: | Homo sapiens, human |
| Tissue: | Embryonic kidney |
| Disease: | Normal |
| Morphology: | Epitheloid cell |
| Growth Properties: | Adherent |
| Ⅴ. Representative Data | |
| |
Figure 1. Recombinant HEK293 cell constitutively expressing TIE2. | |





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