| 名稱(chēng) | CYP2D6*10 Reference Standard | 
| 型號(hào) | CBPA0072 | 
| 報(bào)價(jià) | ![]()  | 
								
| 特點(diǎn) | CYP2D6*10 Reference Standard | 
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  電話(huà):4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
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						基因檢測(cè)標(biāo)準(zhǔn)品 > 用藥指導(dǎo)  >  CBPA0072CYP2D6*10 Reference Standard
            
              
					
				
				
						- 詳細(xì)內(nèi)容
 
| CBPA0072 | |
| Format | Genomic DNA | 
| Description | CYP2D6, cytochrome P450 family 2 subfamily D member 6, is a member of the cytochrome P450 family of monooxygenases that catalyzes drug metabolism (PMID: 28480783). CYP2D6 variants have been associated with risks of various cancers (PMID: 22994728, PMID: 16550168) and may alter the metabolism of tamoxifen in breast cancer patients. | 
| Technical Data | |
| Gene | CYP2D6 | 
| Mutation Type 1 | AA Change: p.S486T | 
| DNA Change: NM_000106.6:c.1457G>C | |
| Chr position (GRCh38): chr22:42126611 | |
| Mutation Type 2 | AA Change: p.P34S | 
| DNA Change: NM_000106.6:c.100C>T | |
| Chr position (GRCh38): chr22:42130692 | |
| Allelic Frequency | 100% | 
| Zygosity | Homozygous | 
| Product Information | |
| Intended Use | Research Use Only | 
| Unit Size | 1ug | 
| Concentration | Download for COA | 
| Purofication | Download for COA | 
| DNA electrophoresis | Download for COA | 
| Sanger sequencing | Figure 1. CYP2D6*10 Reference Standard p.S486T 
 Figure 2. CYP2D6*10 Reference Standard p.P34S  | 
| Storage | 4°C | 
| Expiry | 36 months from the date of manufacture | 





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