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					產品展示  / PRODUCTS
					
						藥靶細胞株 > kinase激酶細胞株  >  CBP73286c-Kit V559A/BaF3
            
              
					
				
				
						- 詳細內容
 
CBP73286  | |
| I. Introduction | |
Cell Line Name:  | c-Kit V559A/BaF3 | 
Host Cell:  | Ba/F3  | 
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) | 
Application:  | Anti-proliferation assay and PD assay  | 
Freeze Medium:  | 90% FBS+10% DMSO  | 
Complete Culture Medium:  | RPMI-1640+10%FBS  | 
Mycoplasma Status:  | Negative  | 
| II.Background | |
KIT V559A lies within the juxtamembrane domain (exon 11) of the Kit protein (PMID: 15837988). V559A results in constitutive phosphorylation of Kit and increased Mapk and Akt activation in patient samples and cultured cells (PMID: 15837988, PMID: 19047099).  | |
| III. Representative Data | |
1.Sanger of c-Kit V559A/BaF3 
  | |
2. Anti-proliferation assay 
 Figure 2. CTG Proliferation Assay of BaF3 c-KIT V559A (C2).  | |






