| 名稱 | c-Kit V560D/BaF3 | 
| 型號 | CBP73235 | 
| 報價 | ![]()  | 
								
| 特點 | c-Kit V560D/BaF3,母細(xì)胞:BaF3,KIT V560D 位于 Kit 蛋白的近膜結(jié)構(gòu)域(外顯子 11)內(nèi)(PMID:19164557)。 V560D 賦予 Kit 功能增強(qiáng),如細(xì)胞培養(yǎng)中 Kit 的組成型磷酸化所示。 | 
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Email: zhangxiangwen@cobioer.com
					產(chǎn)品展示  / PRODUCTS
					
						藥靶細(xì)胞株 > kinase激酶細(xì)胞株  >  CBP73235c-Kit V560D/BaF3
            
              
					
				
				
						- 詳細(xì)內(nèi)容
 
| CBP73235 | |
| I. Introduction | |
Cell Line Name:  | c-Kit V560D/BaF3  | 
Host Cell:  | Ba/F3  | 
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) | 
Application:  | Anti-proliferation assay and PD assay  | 
Freeze Medium:  | 90% FBS+10% DMSO  | 
Complete Culture Medium:  | RPMI-1640+10%FBS  | 
Mycoplasma Status:  | Negative  | 
| II.Background | |
KIT V560D lies within the juxtamembrane domain (exon 11) of the Kit protein (PMID: 19164557). V560D confers a gain of function on Kit, as indicated by constitutive phosphorylation of Kit in cell culture (PMID: 16954519, PMID: 20633291).  | |
| III. Representative Data | |
1. WB of c-Kit V560D/BaF3 
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2.Sanger of c-Kit V560D/BaF3 
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3. Anti-proliferation assay 
 Figure 3. CTG Proliferation Assay of BaF3 C-KIT V560D (C6).  | |







