| 名稱 | c-Kit W557G/BaF3 | 
| 型號 | CBP73293 | 
| 報價 | ![]()  | 
								
| 特點 | c-Kit W557G/BaF3,母細胞:BaF3,KIT W557G 位于 Kit 蛋白 (PMID: 16226710) 的近膜結構域(外顯子 11)內。 W557G 導致細胞培養(yǎng)中 Kit 的組成型磷酸化 (PMID: 23567324),因此,預計會導致 Kit 蛋白功能的獲得。 | 
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					產(chǎn)品展示  / PRODUCTS
					
						藥靶細胞株 > kinase激酶細胞株  >  CBP73293c-Kit W557G/BaF3
            
              
					
				
				
						- 詳細內容
 
CBP73293  | |
| I. Introduction | |
Cell Line Name:  | c-Kit W557G/BaF3 | 
Host Cell:  | Ba/F3  | 
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) | 
Application:  | Anti-proliferation assay and PD assay  | 
Freeze Medium:  | 90% FBS+10% DMSO  | 
Complete Culture Medium:  | RPMI-1640+10%FBS | 
Mycoplasma Status:  | Negative  | 
| II.Background | |
KIT W557G lies within the juxtamembrane domain (exon 11) of the Kit protein (PMID: 16226710). W557G results in constitutive phosphorylation of Kit in cell culture (PMID: 23567324), and therefore, is predicted to lead to a gain of Kit protein function.  | |
| III. Representative Data | |
1. WB of c-Kit W557G/BaF3 
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2. Sanger of c-Kit W557G/BaF3 
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3. Anti-proliferation assay 
 Figure 3. CTG Proliferation Assay of BaF3 c-KIT W557G Cells (C4).  | |
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