| 名稱(chēng) | AI-Edigene® KRAS p.Q61H Reference Standard Pl | 
| 型號(hào) | CBP10430 | 
| 報(bào)價(jià) | ![]()  | 
								
| 特點(diǎn) | AI-Edigene® KRAS p.Q61H Reference Standard Plus | 
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號(hào)碼:
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Email: zhangxiangwen@cobioer.com
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						基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation  >  CBP10430AI-Edigene® KRAS p.Q61H Reference Standard Pl
            
              
					
				
				
						- 詳細(xì)內(nèi)容
 
 CBP10430  | |
| Format | Genomic DNA | 
| Description | KRAS Q61H is a hotspot mutation that lies within a GTP binding region of the Kras protein (UniProt.org). Q61H results in decreased GTPase activity in the Kras protein, increased downstream signaling, and transformation of cultured cells (PMID: 20147967). | 
| Technical Data | |
| DNA Change | c.183A>C | 
| AA Change | p.Q61H | 
| Mutation type | Substitution - Missense | 
| Zygosity | Homozygous | 
| Allelic Frequency | 100% | 
| Transcript | ENST00000311936 | 
| Cosmic ID | COSM554 | 
| Chr position(GRCh37) | chr12:25380275 | 
| Buffer | Tris-EDTA | 
| Product Information | |
| Intended Use | Research Use Only | 
| Unit Size | 1ug | 
| Concentration | Download for COA | 
| Purofication | Download for COA | 
| DNA electrophoresis | Download for COA | 
| Sanger sequencing | 
  | 
| Storage | 4℃ | 
| Expiry | 36 months from the date of manufacture | 
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