| 名稱 | AI-Edigene® NRAS p.G12S Reference Standard Pl | 
| 型號 | CBP10528 | 
| 報價 | ![]()  | 
								
| 特點(diǎn) | AI-Edigene® NRAS p.G12S Reference Standard Plus | 
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Email: zhangxiangwen@cobioer.com
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						基因檢測標(biāo)準(zhǔn)品 > Mutation  >  CBP10528AI-Edigene® NRAS p.G12S Reference Standard Pl
            
              
					
				
				
						- 詳細(xì)內(nèi)容
 
 CBP10528  | |
| Format | Genomic DNA | 
| Description | NRAS G12S is a hotspot mutation that lies within a GTP-binding region of the Nras protein (UniProt.org). G12S confers a loss of function on Nras protein as indicated by increased Erk phosphorylation, increased cell preliferation, and is transforming in culture (PMID: 17823240). | 
| Technical Data | |
| DNA Change: | c.34G>A | 
| AA Change | p.G12S | 
| Mutation type | Substitution - Missense | 
| Zygosity | Homozygous | 
| Allelic Frequency | 100% | 
| Transcript | NM_002524.5 | 
| Cosmic ID | COSM563 | 
| Chr position(GRCh37) | chr1:115258748 | 
| Buffer: | Tris-EDTA | 
| Product Information | |
| Intended Use | Research Use Only | 
| Unit Size | 1ug | 
| Concentration | Download for COA | 
| Purity | Download for COA | 
| DNA electrophoresis | Download for COA | 
| Sanger sequencing | 
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| Storage | 4℃ | 
| Expiry | 36 months from the date of manufacture | 





